BA 440 then U2 2170 at Schiphol
London Heathrow → Amsterdam → Manchester
Timetable, Amsterdam time
16:35BA 440 from London Heathrow at the gate
14:30U2 2170 to Manchester leaves the gate
21 h 55 apart on the timetable, overnight
U2 2170 leaves 21 h 55 after BA 440 arrives on the timetable: more than half a day, so not a connection we count.