KL 1070 then U2 7851 at Schiphol
Southampton → Amsterdam → Manchester
Timetable, Amsterdam time
10:50KL 1070 from Southampton at the gate
08:00U2 7851 to Manchester leaves the gate
21 h 10 apart on the timetable, overnight
U2 7851 leaves 21 h 10 after KL 1070 arrives on the timetable: more than half a day, so not a connection we count.