KL 1504 then U2 2172 at Schiphol
Madrid → Amsterdam → Manchester
Timetable, Amsterdam time
15:40KL 1504 from Madrid at the gate
14:55U2 2172 to Manchester leaves the gate
23 h 15 apart on the timetable, overnight
U2 2172 leaves 23 h 15 after KL 1504 arrives on the timetable: more than half a day, so not a connection we count.