KL 1646 then U2 2172 at Schiphol
Genova → Amsterdam → Manchester
Timetable, Amsterdam time
16:05KL 1646 from Genova at the gate
14:55U2 2172 to Manchester leaves the gate
22 h 50 apart on the timetable, overnight
U2 2172 leaves 22 h 50 after KL 1646 arrives on the timetable: more than half a day, so not a connection we count.