KL 592 then U2 7851 at Schiphol
Johannesburg → Amsterdam → Manchester
Timetable, Amsterdam time
10:10KL 592 from Johannesburg at the gate
08:00U2 7851 to Manchester leaves the gate
21 h 50 apart on the timetable, overnight
U2 7851 leaves 21 h 50 after KL 592 arrives on the timetable: more than half a day, so not a connection we count.