KL 741 then U2 7851 at Schiphol
Cartagena → Amsterdam → Manchester
Timetable, Amsterdam time
10:45KL 741 from Cartagena at the gate
08:00U2 7851 to Manchester leaves the gate
21 h 15 apart on the timetable, overnight
U2 7851 leaves 21 h 15 after KL 741 arrives on the timetable: more than half a day, so not a connection we count.