U2 2161 then BA 8450 at Schiphol
Manchester → Amsterdam → London City
Timetable, Amsterdam time
09:20U2 2161 from Manchester at the gate
08:05BA 8450 to London City leaves the gate
22 h 45 apart on the timetable, overnight
BA 8450 leaves 22 h 45 after U2 2161 arrives on the timetable: more than half a day, so not a connection we count.