U2 2161 then VY 7906 at Schiphol
Manchester → Amsterdam → Valencia
Timetable, Amsterdam time
09:20U2 2161 from Manchester at the gate
21:40VY 7906 to Valencia leaves the gate
12 h 20 apart on the timetable
VY 7906 leaves 12 h 20 after U2 2161 arrives on the timetable: more than half a day, so not a connection we count.