U2 2165 then IB 1346 at Schiphol
Manchester → Amsterdam → Madrid
Timetable, Amsterdam time
17:20U2 2165 from Manchester at the gate
15:50IB 1346 to Madrid leaves the gate
22 h 30 apart on the timetable, overnight
IB 1346 leaves 22 h 30 after U2 2165 arrives on the timetable: more than half a day, so not a connection we count.