U2 2165 then KL 1607 at Schiphol
Manchester → Amsterdam → Rome
Timetable, Amsterdam time
17:20U2 2165 from Manchester at the gate
17:15KL 1607 to Rome leaves the gate
23 h 55 apart on the timetable, overnight
KL 1607 leaves 23 h 55 after U2 2165 arrives on the timetable: more than half a day, so not a connection we count.