GQ 461 then A3 316 at Athens
Karpathos → Athens → Heraklion
Timetable, Athens time
21:15GQ 461 from Karpathos at the gate
15:30A3 316 to Heraklion leaves the gate
18 h 15 apart on the timetable, overnight
A3 316 leaves 18 h 15 after GQ 461 arrives on the timetable: more than half a day, so not a connection we count.