GQ 461 then GQ 388 at Athens
Karpathos → Athens → Thessaloniki
Timetable, Athens time
21:15GQ 461 from Karpathos at the gate
20:25GQ 388 to Thessaloniki leaves the gate
23 h 10 apart on the timetable, overnight
GQ 388 leaves 23 h 10 after GQ 461 arrives on the timetable: more than half a day, so not a connection we count.