EC 3749 then LA 5778 at Barcelona
Milan → Barcelona → Valletta
Timetable, Barcelona time
21:30EC 3749 from Milan at the gate
13:00LA 5778 to Valletta leaves the gate
15 h 30 apart on the timetable, overnight
LA 5778 leaves 15 h 30 after EC 3749 arrives on the timetable: more than half a day, so not a connection we count.