EC 7154 then FR 7543 at Barcelona
Milan → Barcelona → Manchester
Timetable, Barcelona time
23:15EC 7154 from Milan at the gate
11:35FR 7543 to Manchester leaves the gate
12 h 20 apart on the timetable, overnight
FR 7543 leaves 12 h 20 after EC 7154 arrives on the timetable: more than half a day, so not a connection we count.