FR 4586 then FR 7543 at Barcelona
Porto → Barcelona → Manchester
Timetable, Barcelona time
21:10FR 4586 from Porto at the gate
11:35FR 7543 to Manchester leaves the gate
14 h 25 apart on the timetable, overnight
FR 7543 leaves 14 h 25 after FR 4586 arrives on the timetable: more than half a day, so not a connection we count.