FR 5271 then VY 6016 at Barcelona
Manchester → Barcelona → Rome
Timetable, Barcelona time
21:55FR 5271 from Manchester at the gate
18:25VY 6016 to Rome leaves the gate
20 h 30 apart on the timetable, overnight
VY 6016 leaves 20 h 30 after FR 5271 arrives on the timetable: more than half a day, so not a connection we count.