QR 3653 then FR 6597 at Barcelona
Rome → Barcelona → Manchester
Timetable, Barcelona time
14:25QR 3653 from Rome at the gate
10:25FR 6597 to Manchester leaves the gate
20 h apart on the timetable, overnight
FR 6597 leaves 20 h after QR 3653 arrives on the timetable: more than half a day, so not a connection we count.