QR 3744 then EC 7205 at Barcelona
Milan → Barcelona → Southampton
Timetable, Barcelona time
16:45QR 3744 from Milan at the gatealso IB 5357, LL 5357, VY 6045
13:05EC 7205 to Southampton leaves the gate
20 h 20 apart on the timetable, overnight
EC 7205 leaves 20 h 20 after QR 3744 arrives on the timetable: more than half a day, so not a connection we count.