AF 1001 then U2 3812 at Charles de Gaulle
Madrid → Paris → Milan
Timetable, Paris time
12:10AF 1001 from Madrid at the gatealso AR 7830
10:45U2 3812 to Milan leaves the gate
22 h 35 apart on the timetable, overnight
U2 3812 leaves 22 h 35 after AF 1001 arrives on the timetable: more than half a day, so not a connection we count.