AF 7421 then U2 4541 at Charles de Gaulle
Toulouse → Paris → Milan
Timetable, Paris time
08:40AF 7421 from Toulouse at the gate
06:00U2 4541 to Milan leaves the gate
21 h 20 apart on the timetable, overnight
U2 4541 leaves 21 h 20 after AF 7421 arrives on the timetable: more than half a day, so not a connection we count.