AZ 324 then U2 2110 at Charles de Gaulle
Rome → Paris → Manchester
Timetable, Paris time
17:25AZ 324 from Rome at the gate
16:00U2 2110 to Manchester leaves the gate
22 h 35 apart on the timetable, overnight
U2 2110 leaves 22 h 35 after AZ 324 arrives on the timetable: more than half a day, so not a connection we count.