U2 4630 then AF 474 at Charles de Gaulle
Manchester → Paris → Tocumen
Timetable, Paris time
22:15U2 4630 from Manchester at the gate
14:55AF 474 to Tocumen leaves the gate
16 h 40 apart on the timetable, overnight
AF 474 leaves 16 h 40 after U2 4630 arrives on the timetable: more than half a day, so not a connection we count.