AA 2110 then AA 5335 at Charlotte
Wilmington → Charlotte → South Bend
Timetable, Charlotte time
16:48AA 2110 from Wilmington at the gate
15:48AA 5335 to South Bend leaves the gate
23 h apart on the timetable, overnight
AA 5335 leaves 23 h after AA 2110 arrives on the timetable: more than half a day, so not a connection we count.