AA 2486 then AA 5135 at Charlotte
St Louis → Charlotte → Charleston (South Carolina)
Timetable, Charlotte time
16:49AA 2486 from St Louis at the gate
15:44AA 5135 to Charleston (South Carolina) leaves the gate
22 h 55 apart on the timetable, overnight
AA 5135 leaves 22 h 55 after AA 2486 arrives on the timetable: more than half a day, so not a connection we count.