AA 5390 then AA 6097 at Charlotte
Lexington → Charlotte → Greenville-Spartanburg
Timetable, Charlotte time
09:22AA 5390 from Lexington at the gate
07:15AA 6097 to Greenville-Spartanburg leaves the gate
21 h 53 apart on the timetable, overnight
AA 6097 leaves 21 h 53 after AA 5390 arrives on the timetable: more than half a day, so not a connection we count.