AA 5453 then AA 5464 at Charlotte
Manchester → Charlotte → Wilkes-Barre
Timetable, Charlotte time
09:45AA 5453 from Manchester at the gate
22:35AA 5464 to Wilkes-Barre leaves the gate
12 h 50 apart on the timetable
AA 5464 leaves 12 h 50 after AA 5453 arrives on the timetable: more than half a day, so not a connection we count.