AA 5457 then AA 2410 at Charlotte
Manchester → Charlotte → San Francisco
Timetable, Charlotte time
18:18AA 5457 from Manchester at the gate
18:00AA 2410 to San Francisco leaves the gate
23 h 42 apart on the timetable, overnight
AA 2410 leaves 23 h 42 after AA 5457 arrives on the timetable: more than half a day, so not a connection we count.