AA 5627 then AA 5543 at Charlotte
Charleston (South Carolina) → Charlotte → Pittsburgh
Timetable, Charlotte time
11:35AA 5627 from Charleston (South Carolina) at the gate
08:35AA 5543 to Pittsburgh leaves the gate
21 h apart on the timetable, overnight
AA 5543 leaves 21 h after AA 5627 arrives on the timetable: more than half a day, so not a connection we count.