DL 4176 then DL 5354 at Detroit
Appleton → Detroit → Greenville-Spartanburg
Timetable, Detroit time
09:22DL 4176 from Appleton at the gate
08:31DL 5354 to Greenville-Spartanburg leaves the gate
23 h 09 apart on the timetable, overnight
DL 5354 leaves 23 h 09 after DL 4176 arrives on the timetable: more than half a day, so not a connection we count.