BQ 2322 then FR 4861 at Fiumicino
Manchester → Rome → Catania
Timetable, Rome time
20:25BQ 2322 from Manchester at the gate
12:50FR 4861 to Catania leaves the gate
16 h 25 apart on the timetable, overnight
FR 4861 leaves 16 h 25 after BQ 2322 arrives on the timetable: more than half a day, so not a connection we count.