U2 2123 then AZ 610 at Fiumicino
Manchester → Rome → New York JFK
Timetable, Rome time
20:10U2 2123 from Manchester at the gate
14:55AZ 610 to New York JFK leaves the gate
18 h 45 apart on the timetable, overnight
AZ 610 leaves 18 h 45 after U2 2123 arrives on the timetable: more than half a day, so not a connection we count.