U2 2123 then FR 9601 at Fiumicino
Manchester → Rome → Madrid
Timetable, Rome time
20:10U2 2123 from Manchester at the gate
18:45FR 9601 to Madrid leaves the gate
22 h 35 apart on the timetable, overnight
FR 9601 leaves 22 h 35 after U2 2123 arrives on the timetable: more than half a day, so not a connection we count.