U2 2123 then SN 3182 at Fiumicino
Manchester → Rome → Brussels
Timetable, Rome time
20:10U2 2123 from Manchester at the gate
18:00SN 3182 to Brussels leaves the gate
21 h 50 apart on the timetable, overnight
SN 3182 leaves 21 h 50 after U2 2123 arrives on the timetable: more than half a day, so not a connection we count.