U2 4411 then U2 2124 at Fiumicino
Lyon → Rome → Manchester
Timetable, Rome time
12:40U2 4411 from Lyon at the gate
11:05U2 2124 to Manchester leaves the gate
22 h 25 apart on the timetable, overnight
U2 2124 leaves 22 h 25 after U2 4411 arrives on the timetable: more than half a day, so not a connection we count.