U2 6104 then IB 650 at Fiumicino
Munich → Rome → Madrid
Timetable, Rome time
16:15U2 6104 from Munich at the gate
14:45IB 650 to Madrid leaves the gate
22 h 30 apart on the timetable, overnight
IB 650 leaves 22 h 30 after U2 6104 arrives on the timetable: more than half a day, so not a connection we count.