DE 1669 then EN 1398 at Frankfurt
Heraklion → Frankfurt am Main → Prague
Timetable, Frankfurt am Main time
17:50DE 1669 from Heraklion at the gate
17:15EN 1398 to Prague leaves the gate
23 h 25 apart on the timetable, overnight
EN 1398 leaves 23 h 25 after DE 1669 arrives on the timetable: more than half a day, so not a connection we count.