DE 2227 then DE 1668 at Frankfurt
Punta Cana → Frankfurt am Main → Heraklion
Timetable, Frankfurt am Main time
11:50DE 2227 from Punta Cana at the gate
09:40DE 1668 to Heraklion leaves the gate
21 h 50 apart on the timetable, overnight
DE 1668 leaves 21 h 50 after DE 2227 arrives on the timetable: more than half a day, so not a connection we count.