DE 4483 then DE 1668 at Frankfurt
Prague → Frankfurt am Main → Heraklion
Timetable, Frankfurt am Main time
12:55DE 4483 from Prague at the gate
09:40DE 1668 to Heraklion leaves the gate
20 h 45 apart on the timetable, overnight
DE 1668 leaves 20 h 45 after DE 4483 arrives on the timetable: more than half a day, so not a connection we count.