DE 4483 then DE 2228 at Frankfurt
Prague → Frankfurt am Main → Punta Cana
Timetable, Frankfurt am Main time
12:55DE 4483 from Prague at the gate
11:50DE 2228 to Punta Cana leaves the gate
22 h 55 apart on the timetable, overnight
DE 2228 leaves 22 h 55 after DE 4483 arrives on the timetable: more than half a day, so not a connection we count.