EN 311 then DE 1668 at Frankfurt
Firenze → Frankfurt am Main → Heraklion
Timetable, Frankfurt am Main time
11:55EN 311 from Firenze at the gate
09:40DE 1668 to Heraklion leaves the gate
21 h 45 apart on the timetable, overnight
DE 1668 leaves 21 h 45 after EN 311 arrives on the timetable: more than half a day, so not a connection we count.