X3 4605 then DE 1668 at Frankfurt
Kos → Frankfurt am Main → Heraklion
Timetable, Frankfurt am Main time
12:05X3 4605 from Kos at the gate
09:40DE 1668 to Heraklion leaves the gate
21 h 35 apart on the timetable, overnight
DE 1668 leaves 21 h 35 after X3 4605 arrives on the timetable: more than half a day, so not a connection we count.