EC 7668 then EC 7645 at Lisbon
Luxembourg → Lisbon → Madrid
Timetable, Lisbon time
21:55EC 7668 from Luxembourg at the gate
15:00EC 7645 to Madrid leaves the gate
17 h 05 apart on the timetable, overnight
EC 7645 leaves 17 h 05 after EC 7668 arrives on the timetable: more than half a day, so not a connection we count.