EC 7668 then U2 7651 at Lisbon
Luxembourg → Lisbon → Madrid
Timetable, Lisbon time
21:55EC 7668 from Luxembourg at the gate
19:05U2 7651 to Madrid leaves the gate
21 h 10 apart on the timetable, overnight
U2 7651 leaves 21 h 10 after EC 7668 arrives on the timetable: more than half a day, so not a connection we count.