TP 1921 then FR 2253 at Lisbon
Porto → Lisbon → Manchester
Timetable, Lisbon time
09:25TP 1921 from Porto at the gate
21:45FR 2253 to Manchester leaves the gate
12 h 20 apart on the timetable
FR 2253 leaves 12 h 20 after TP 1921 arrives on the timetable: more than half a day, so not a connection we count.