U2 7638 then FR 9441 at Lisbon
Nantes → Lisbon → Madrid
Timetable, Lisbon time
22:45U2 7638 from Nantes at the gate
20:50FR 9441 to Madrid leaves the gate
22 h 05 apart on the timetable, overnight
FR 9441 leaves 22 h 05 after U2 7638 arrives on the timetable: more than half a day, so not a connection we count.