AV 16 then FR 572 at Madrid
Medellín → Madrid → Porto
Timetable, Madrid time
13:55AV 16 from Medellín at the gatealso EY 2608, EK 3804, CA 5310
11:15FR 572 to Porto leaves the gate
21 h 20 apart on the timetable, overnight
FR 572 leaves 21 h 20 after AV 16 arrives on the timetable: more than half a day, so not a connection we count.