EC 4389 then BA 7050 at Madrid
Lyon → Madrid → London Heathrow
Timetable, Madrid time
17:20EC 4389 from Lyon at the gate
16:45BA 7050 to London Heathrow leaves the gate
23 h 25 apart on the timetable, overnight
BA 7050 leaves 23 h 25 after EC 4389 arrives on the timetable: more than half a day, so not a connection we count.