EW 3180 then FR 6815 at Madrid
Prague → Madrid → Manchester
Timetable, Madrid time
13:05EW 3180 from Prague at the gate
10:40FR 6815 to Manchester leaves the gate
21 h 35 apart on the timetable, overnight
FR 6815 leaves 21 h 35 after EW 3180 arrives on the timetable: more than half a day, so not a connection we count.