EY 4380 then FR 2753 at Madrid
Santo Domingo → Madrid → Milan
Timetable, Madrid time
11:10EY 4380 from Santo Domingo at the gatealso SK 8398, TK 9064
08:50FR 2753 to Milan leaves the gate
21 h 40 apart on the timetable, overnight
FR 2753 leaves 21 h 40 after EY 4380 arrives on the timetable: more than half a day, so not a connection we count.