FR 2437 then U2 7646 at Madrid
Rome → Madrid → Lisbon
Timetable, Madrid time
09:00FR 2437 from Rome at the gate
21:25U2 7646 to Lisbon leaves the gate
12 h 25 apart on the timetable
U2 7646 leaves 12 h 25 after FR 2437 arrives on the timetable: more than half a day, so not a connection we count.